| 1 |  Dylan SampsonD. SampsonCLE · 8 games | 1,164 | 17 | 7.8 | 145.5 | 8 | 150 | 67 | 363 | 25 | 18 | 0 |
| 2 |  Travis Etienne JrT. Etienne JrNO · 7 games | 1,123 | 14 | 10.5 | 160.4 | 7 | 107 | 84 | 344 | 17 | 14 | 2 |
| 3 |  Kyren WilliamsK. WilliamsLAR · 7 games | 928 | 8 | 8.4 | 132.6 | 7 | 111 | 65 | 353 | 40 | 8 | 1 |
| 4 |  Jonathan TaylorJ. TaylorIND · 7 games | 873 | 9 | 7.3 | 124.7 | 7 | 119 | 66 | 250 | 36 | 12 | 0 |
| 5 |  Eli HeidenreichE. HeidenreichPIT · 8 games | 858 | 7 | 6.7 | 107.3 | 8 | 128 | 39 | 200 | 10 | 8 | 0 |
| 6 |  Bijan RobinsonB. RobinsonATL · 7 games | 827 | 13 | 7.6 | 118.1 | 7 | 109 | 90 | 171 | 16 | 8 | 1 |
| 7 |  Breece HallB. HallNYJ · 7 games | 810 | 11 | 6.8 | 115.7 | 7 | 119 | 78 | 256 | 25 | 11 | 1 |
| 8 |  TreVeyon HendersonT. HendersonNE · 7 games | 802 | 9 | 7.9 | 114.6 | 7 | 102 | 88 | 186 | 22 | 11 | 2 |
| 9 |  Jahmyr GibbsJ. GibbsDET · 7 games | 800 | 11 | 9.3 | 114.3 | 7 | 86 | 92 | 203 | 15 | 9 | 0 |
| 10 |  Eddie BurksE. BurksGB · 8 games | 789 | 7 | 7.7 | 98.6 | 8 | 102 | 76 | 235 | 17 | 9 | 1 |
| 11 |  Shakim MeadowsS. MeadowsTEN · 8 games | 780 | 7 | 6.8 | 97.5 | 8 | 114 | 76 | 180 | 16 | 11 | 2 |
| 12 |  Kenneth WalkerK. WalkerKC · 8 games | 776 | 8 | 7.7 | 97.0 | 8 | 101 | 75 | 234 | 28 | 8 | 0 |
| 13 |  James Cook IIIJ. Cook IIIBUF · 8 games | 762 | 11 | 6.1 | 95.3 | 8 | 124 | 62 | 203 | 14 | 5 | 1 |
| 14 |  Jimmy HuntingtonJ. HuntingtonCHI · 7 games | 757 | 8 | 5.9 | 108.1 | 7 | 128 | 78 | 148 | 14 | 8 | 0 |
| 15 |  Saquon BarkleyS. BarkleyPHI · 7 games | 745 | 10 | 8.2 | 106.4 | 7 | 91 | 71 | 283 | 33 | 10 | 1 |
| 16 |  Demond ClaiborneD. ClaiborneMIN · 7 games | 737 | 8 | 5.5 | 105.3 | 7 | 133 | 68 | 223 | 23 | 5 | 0 |
| 17 |  Chase BrownC. BrownCIN · 6 games | 731 | 6 | 6.6 | 121.8 | 6 | 110 | 58 | 166 | 10 | 7 | 1 |
| 18 |  Christian McCaffreyC. McCaffreySF · 7 games | 728 | 10 | 6.1 | 104.0 | 7 | 119 | 65 | 233 | 27 | 4 | 2 |
| 19 |  Jadarian PriceJ. PriceSEA · 7 games | 681 | 8 | 5.6 | 97.3 | 7 | 121 | 30 | 210 | 20 | 6 | 0 |
| 20 |  Bucky IrvingB. IrvingCAR · 7 games | 676 | 7 | 8.6 | 96.6 | 7 | 79 | 96 | 115 | 10 | 7 | 0 |
| 21 |  Ashton JeantyA. JeantyLV · 8 games | 662 | 6 | 4.5 | 82.8 | 8 | 146 | 41 | 206 | 16 | 4 | 0 |
| 22 |  RJ HarveyR. HarveyDEN · 6 games | 657 | 8 | 6.8 | 109.5 | 6 | 96 | 100 | 150 | 14 | 7 | 0 |
| 23 |  Cam SkatteboC. SkatteboNYG · 7 games | 614 | 4 | 6.1 | 87.7 | 7 | 101 | 46 | 314 | 30 | 6 | 0 |
| 24 |  De'Von AchaneD. AchaneMIA · 6 games | 598 | 4 | 5.6 | 99.7 | 6 | 106 | 78 | 158 | 26 | 6 | 1 |
| 25 |  Bhayshul TutenB. TutenJAX · 6 games | 583 | 7 | 7.1 | 97.2 | 6 | 82 | 77 | 273 | 16 | 4 | 1 |
| 26 |  Quinshon JudkinsQ. JudkinsHOU · 7 games | 520 | 3 | 6.3 | 74.3 | 7 | 83 | 50 | 138 | 15 | 5 | 3 |
| 27 |  Kewan LacyK. LacyTB · 7 games | 499 | 6 | 5.1 | 71.3 | 7 | 97 | 81 | 107 | 16 | 3 | 0 |
| 28 |  Jacory Croskey-MerrittJ. Croskey-MerrittWSH · 5 games | 477 | 5 | 6.9 | 95.4 | 5 | 69 | 59 | 111 | 9 | 5 | 1 |
| 29 |  Jaydon BlueJ. BlueDAL · 5 games | 476 | 2 | 9.3 | 95.2 | 5 | 51 | 62 | 122 | 12 | 8 | 0 |
| 30 |  Joe MixonJ. MixonBAL · 8 games | 472 | 5 | 6.6 | 59.0 | 8 | 71 | 61 | 143 | 20 | 4 | 1 |
| 31 |  Javonte WilliamsJ. WilliamsDAL · 5 games | 426 | 4 | 7.0 | 85.2 | 5 | 61 | 81 | 186 | 17 | 4 | 0 |
| 32 |  Jeremiyah LoveJ. LoveARI · 8 games | 354 | 4 | 5.2 | 44.3 | 8 | 68 | 28 | 101 | 15 | 3 | 1 |
| 33 |  Lamar JacksonL. JacksonBAL · 8 games | 342 | 2 | 5.4 | 42.8 | 8 | 63 | 30 | 72 | 5 | 3 | 1 |
| 34 |  Omarion HamptonO. HamptonLAC · 6 games | 330 | 5 | 4.9 | 55.0 | 6 | 67 | 29 | 108 | 11 | 3 | 0 |